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The clinical utility of sperm DNA integrity testing

Book ID
116474428
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
89 KB
Volume
90
Category
Article
ISSN
1556-5653

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โœฆ Synopsis

Sperm DNA damage is more common in infertile men and may contribute to poor reproductive performance. However, current methods for evaluating sperm DNA integrity do not reliably predict treatment outcomes, and no treatment for abnormal DNA integrity has proven clinical value.

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Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage tha