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The clinical spectrum of bruton’s agammaglobulinemia

✍ Scribed by Donn M. Stewart; Lan Tian; David L. Nelson

Book ID
107532581
Publisher
Current Science Inc.
Year
2001
Tongue
English
Weight
433 KB
Volume
1
Category
Article
ISSN
1529-7322

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X-linked agammaglobulinemia (XLA) is a primary immunodeficiency of the B-cell compartment caused by a defective gene encoding for the tyrosine kinase (btk) essential for B cell differentiation. Affected males undergo recurrent pyogenic infections and deficient immunoglobulin production. Peripheral b