๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The clinical manipulation of angiogenesis: pathology, side-effects, surprises, and opportunities with novel human therapies

โœ Scribed by Thompson, W. Douglas; Li, William W.; Maragoudakis, Michael

Book ID
101221607
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
111 KB
Volume
190
Category
Article
ISSN
0022-3417

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โœฆ Synopsis

The ยฎrst phase of angiogenesis research has provided knowledge of the basic pathobiology of angiogenesis and its manipulation in models, mouse, and man. The ยฎrst line of therapeutic substances has been devised and is now in clinical trials. New lessons are being learned from clinical observations. Unexpected side-effects are being noted, particularly affecting the nervous system. Other side-effects may be anticipated from a sound knowledge of clinical pathology and recognition of the commonality of angiogenesis to multiple disease mechanisms, but these may be tolerable or avoidable. Angiogenesis researchers await further feedback and ideas from the clinic to stimulate the next phase of basic and applied research.

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