To detect mutations in the thiopurine S-methyltransferase gene (TPMT), we have developed a strategy based on single-strand conformation polymorphism (SSCP) analysis of the gene amplified by polymerase chain reaction (PCR). The sensitivity of the method was first evaluated by analyzing DNA samples fr
The Clinical Impact of Thiopurine Methyltransferase Polymorphisms on Thiopurine Treatment
β Scribed by S. A. Coulthard; E. C. Matheson; A. G. Hall; L. A. Hogarth
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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