𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Clinical Impact of Thiopurine Methyltransferase Polymorphisms on Thiopurine Treatment

✍ Scribed by S. A. Coulthard; E. C. Matheson; A. G. Hall; L. A. Hogarth


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Detection of known and new mutations in
✍ Catherine Spire-Vayron de la Moureyre; HervΓ© DebuysΓ¨re; Nadda Sabbagh; Delphine πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 467 KB πŸ‘ 2 views

To detect mutations in the thiopurine S-methyltransferase gene (TPMT), we have developed a strategy based on single-strand conformation polymorphism (SSCP) analysis of the gene amplified by polymerase chain reaction (PCR). The sensitivity of the method was first evaluated by analyzing DNA samples fr

How to assess the clinical impact of tre
✍ Helena Chmura Kraemer; Ellen Frank; David J. Kupfer πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 209 KB

While randomized clinical trials (RCTs) should provide the basis for evidence-based medicine, as currently designed and analyzed, they often mislead clinical decision-making. Comparative effectiveness evaluation of two treatments [Treatment 1 (T1) versus Treatment 2 (T2)] should not be determined by

Estimating treatment effects in randomiz
✍ Barton H. Hamilton πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 150 KB πŸ‘ 1 views

## Abstract This paper assesses the causal impact of late‐term (8th month) maternal smoking on birthweight using data from a randomized clinical trial, in which some women were encouraged not to smoke, while others were not. The estimation of treatment effects in this case is made difficult as a re

The effects of the dopamine and serotoni
✍ Helen Lavretsky; Prabha Siddarth; Anand Kumar; Charles F. Reynolds III πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 85 KB πŸ‘ 2 views

## Abstract ## Background The authors examined the role of dopamine and serotonin transporter genetic polymorphisms in clinical and cognitive features of subjects with late‐life depression, and in preferential treatment response to the combination of methylphenidate and citalopram. ## Method The