The clinical application of array CGH for the detection of chromosomal defects in 20,126 unselected newborns
✍ Scribed by Sang-Jin Park, Eun Hye Jung, Ran-Suk Ryu, Hyun Woong Kang…
- Book ID
- 120698099
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 231 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1755-8166
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## Abstract To evaluate whether copy number alterations (CNAs) are present that may contribute to disease development and/or progression of childhood myelodysplastic syndromes (MDS), 36 pediatric MDS patients were analyzed using array‐based comparative genome hybridization (aCGH). In addition to mo
## Abstract Chromosome analysis is an important component to the diagnosis of congenital anomalies, developmental delay, and mental retardation. Routine chromosome analysis identifies aneuploidy and structural rearrangements greater than 5 Mb but cannot identify abnormalities of the telomeric regio