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The Cleavage of Ethers by Hydrogen Bromide

โœ Scribed by Burwell, Robert L.; Fuller, Milton E.


Book ID
126149425
Publisher
American Chemical Society
Year
1957
Tongue
English
Weight
662 KB
Volume
79
Category
Article
ISSN
0002-7863

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Reaction of menthol-MEM ether with Me2BBr gave, after quenching with sat. aq. sodium bicarbonate in the absence of tetrahydrofuran (see Experimental), a mixture of menthol and formaldehyde-dimenthol ketal in 61 and 15% yield, respectively. We have previously cleaved this acetonide using HCl(5N)-EtO