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The circadian rhythm of biochemical markers of bone resorption is normally synchronized in breast cancer patients with bone lytic metastases independently of tumor load

✍ Scribed by Daniele Generali; Alfredo Berruti; Marco Tampellini; Andrea Dovio; Sara Tedoldi; Simone Bonardi; Marcello Tucci; Giovanni Allevi; Sergio Aguggini; Manuela Milani; Alberto Bottini; Luigi Dogliotti; Alberto Angeli

Book ID: 116319776
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 276 KB
Volume: 40
Category: Article
ISSN: 8756-3282
DOI: 10.1016/j.bone.2006.06.023

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## Abstract ## BACKGROUND. For patients with bone metastases, high N‐telopeptide of type I collagen (NTX) levels correlate with increased risks of skeletal‐related events and death. However, the relation between NTX decreases and clinical benefits is unclear. ## METHODS. Correlations between NTX