Insulin-like growth factor-I-dependent s
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Alberto M. Martelli; Lucio Cocco; Renato Bareggi; Giovanna Tabellini; Riccardo R
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Article
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1999
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John Wiley and Sons
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English
⚖ 165 KB
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Swiss 3T3 mouse fibroblasts were exposed to 10 microM colchicine to disrupt microtubules, then stimulated with insulin-like growth factor-I. Immunoprecipitation experiments showed that insulin-like growth factor-I receptor and insulin receptor substrate-1 were tyrosine phosphorylated to the same ext