The chorioallantoic membrane of the chick embryo as a simple model for the study of the angiogenic and inflammatory response to biomaterials
✍ Scribed by G. Zwadlo-Klarwasser; K. Görlitz; B. Hafemann; D. Klee; B. Klosterhalfen
- Book ID
- 110270872
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 157 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0957-4530
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Current in vivo models for testing biomaterials are time and labor intensive as well as expensive. This article describes a new approach for testing biomaterials in vivo using the chorioallantoic membrane (CAM) of the developing chicken embryo, as an alternative to the traditional mammalian models.
## Abstract One of the major obstacles in developing rationale strategies to control inflammation and fibrosis surrounding implants is the lack of a simple and inexpensive __in vivo__ model to screen tissue reactions to various biomaterials and implants. To begin to fill this gap, we have developed