The cholesterol saturation index of human bile
β Scribed by Swell, Leon ;Bell, C. Cooper ;Gregory, Daniel H. ;Vlahcevic, Z. Reno
- Book ID
- 112475949
- Publisher
- Springer-Verlag
- Year
- 1974
- Weight
- 350 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0002-9211
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π SIMILAR VOLUMES
## I We investigated whether bile concentration influenced cholesterol saturation index or nucleation time of cholesterol monohydrate crystals in a large number of gallbladder bile samples. Pigment stone patients never had cholesterol crystals in their fresh biles, and nucleation time was always l
We tested the possibility that simvastatin, a competitive inhibitor of HMG-CoA reductase related to mevinolin, might alter cholesterol saturation of gallbladder bile. Ten patients with Type IIa or IIb hypercholesterolemia underwent bile sampling before, and again after, treatment with 20 or 40 mg pe