The relative efficacy of Photofrin w -based photodynamic therapy (PDT) has been compared with that of the second-generation photosensitizers 5-aminolevulinic acid (ALA), sulfonated chloro-aluminum phthalocyanine (AlPcS n ), benzoporphyrin derivative monoacid ring A (BPD-MA), and lutetium texaphyrin
The chick chorioallantoic membrane (CAM) as an in vivo model for photodynamic therapy
โ Scribed by V. Gottfried; E.S. Lindenbaum; S. Kimel
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 260 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1011-1344
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Current in vivo models for testing biomaterials are time and labor intensive as well as expensive. This article describes a new approach for testing biomaterials in vivo using the chorioallantoic membrane (CAM) of the developing chicken embryo, as an alternative to the traditional mammalian models.
The chick chorioallantoic membrane (CAM) model was used to study vascular effects of photodynamic therapy (PDT) and hyperthermia (HPT) and the synergism of these modalities. The CAM is a convenient medium for monitoring the modifications of the vasculature. It is possible to view the CAM and to exam
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