The chemistry of the opioid receptor binding sites : Josef Rudinger Memorial Lecture 2002

✍ Scribed by Prof. Kálmán Medzihradszky

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: English
• Weight: 225 KB
• Volume: 9
• Category: Article
• ISSN: 1075-2617
• DOI: 10.1002/psc.469

✦ Synopsis

Abstract

Since the discovery of the opioid receptors and their endogenous ligands an immense research work has been devoted to the exploration of their specificity, the mechanism of ligand binding and ligand–receptor interactions. One of the main goals has been the location and characterization of the binding sites. The present review compiles the results achieved in this field in the last quarter of a century, and puts some questions concerning the success of these efforts. Copyright © 2003 European Peptide Society and John Wiley & Sons, Ltd.