The chemistry of 3-ketotetrahydrofurans I: Syntheses of 3-ketotetrahydrofuran by oxidation

✍ Scribed by J. H. Sperna Weiland; H. Dijkstra; A. B. Pik

• Book ID: 104586650
• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 303 KB
• Volume: 82
• Category: Article
• ISSN: 0165-0513
• DOI: 10.1002/recl.19630820703

✦ Synopsis

Abstract

3‐Ketotetrahydrofuran (II) has been obtained spectroscopically as well as gas‐chromatographically pure. A major modification in the dichromate‐sulphuric acid oxidation of the starting alcohol (I) has almost doubled the yield to 60%.

The chromium trioxide‐pyridine oxidation of (I) is described for the first time and yields as high as 70% are obtained. The NMR spectrum of (II) is reported.