𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The chemical biology of copper

✍ Scribed by Bo G Malmström; Johan Leckner

Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
690 KB
Volume
2
Category
Article
ISSN
1367-5931

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✦ Synopsis

Major progress was made in 1997 in the understanding of the biological transport of copper. Blue copper and CuA sites have very low electron transfer reorganization energies. The mechanisms of copper-containing oxygenases and oxidases have been clarified by recent crystal structure determinations. Protein folding has been shown to tune the reduction potentials of blue copper proteins by hydrophobic encapsulation of the active sites and strict control of the axial ligation.

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