𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The characteristics of human NKT cells in lung cancer—CD1d independent cytotoxicity against lung cancer cells by NKT cells and decreased human NKT cell response in lung cancer patients

✍ Scribed by Jun Konishi; Koichi Yamazaki; Hiroshi Yokouchi; Naofumi Shinagawa; Kazuya Iwabuchi; Masaharu Nishimura

Book ID
116530655
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
331 KB
Volume
65
Category
Article
ISSN
0198-8859

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Invariant NKT cells and CD1d+ cells amas
Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity
✍ Lydia Lynch; Donal O'Shea; Desmond C. Winter; Justin Geoghegan; Derek G. Doherty 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 413 KB

## Abstract Invariant NKT (iNKT) cells recognize lipid antigens presented by CD1d and respond rapidly by killing tumor cells and release cytokines that activate and regulate adaptive immune responses. They are essential for tumor rejection in various mouse models, but clinical trials in humans invo

Preserved IFN-α production of circulatin
Preserved IFN-α production of circulating Vα24 NKT cells in primary lung cancer patients
✍ Shinichiro Motohashi; Seiichiro Kobayashi; Toshihiro Ito; Kumiko K. Magara; Osam 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 153 KB

## Abstract Human Vα24 NKT cells bearing an invariant Vα24JαQ antigen receptor, the counterpart of murine Vα14 NKT cells, are activated by a specific ligand, α‐GalCer, in a CD1d‐dependent manner. Here, we demonstrate decreased numbers of circulating Vα24 NKT cells in patients with primary lung canc