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The changes of learning and memory abilities and insulin signal pathway on hippocampal neurons of diabetic mice

✍ Scribed by Rong Wang; Jie Yao; Shuli Sheng

Book ID: 118467171
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 49 KB
Volume: 7
Category: Article
ISSN: 1552-5260
DOI: 10.1016/j.jalz.2011.05.301

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## Abstract We have evaluated the effect of peripheral insulin deficiency on brain insulin pathway activity in a mouse model of type 1 diabetes, the parallels with Alzheimer's disease (AD), and the effect of treatment with insulin. Nine weeks of insulin‐deficient diabetes significantly impaired the