𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The challenge of the combined use of synthetic antigens and synthetic adjuvants

✍ Scribed by Sela, Michael ;Mozes, Edna


Book ID
104661428
Publisher
Springer
Year
1979
Tongue
English
Weight
930 KB
Volume
2
Category
Article
ISSN
0344-4325

No coin nor oath required. For personal study only.

✦ Synopsis


Synthetic antigens are simple compounds, the chemistry of which is not only known but also to a large extent controlled at will. Another milestone of modern immunochemistry is the recent availability of synthetic water-soluble adjuvants. It is the belief of the authors that an approach combining the two synthetic types of compounds, whether by administering them together or by linking them covalently to each other, may lead to products that will not only lead to a better understanding of immunologic phenomena but may be also of significant pharmacologic value.


πŸ“œ SIMILAR VOLUMES


The ten grand challenges of synthetic li
✍ Manuel Porcar; Antoine Danchin; Victor de Lorenzo; Vitor A. dos Santos; Natalio πŸ“‚ Article πŸ“… 2011 πŸ› Springer Netherlands 🌐 English βš– 182 KB
The macrophage, target cell of the synth
✍ M. Fevrier; J. L. Birrien; C. Leclerc; L. Chedid; P. Liacopoulos πŸ“‚ Article πŸ“… 1978 πŸ› John Wiley and Sons 🌐 English βš– 545 KB

## Abstract The mechanism of adjuvant activity of the synthetic glycopeptide N‐acetylmuramyl‐L‐alanyl‐D‐isoglutamine or muramyl dipeptide (MDP) was studied using __in vitro__ plaque‐forming cell (PFC) response to sheep erythrocytes (SRBC). Addition of MDP to DBA/2 mouse spleen cell cultures resulte

The synthetic use of Ξ±-ferrocenylcarbeni
✍ Stig Allenmark πŸ“‚ Article πŸ“… 1974 πŸ› Elsevier Science 🌐 French βš– 189 KB

The remarkable stability of a-ferrocenylcarbenium ions is evident from solvolysis experiments 1 as well as generation from carbinol precursors in acid media and direct spectroscopic observation. 2 The latter has also permitted determination of pKR-values for the carbinol-carbenium ion equilibria. 3