๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The challenge of drug discovery of a GPCR target: Analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists

โœ Scribed by A.A. Hancock


Book ID
113487807
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
459 KB
Volume
71
Category
Article
ISSN
0006-2952

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Discovery of potent and selective histam
โœ H.G.F. Richter; C. Freichel; J. Huwyler; T. Nakagawa; M. Nettekoven; J.-M. Planc ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 453 KB

A novel series of potent histamine H(3) receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold has been discovered. Several compounds display high selectivity over other histamine receptor subtypes and have favorable physicochemical properties, low potential for CY