Cerebroside sulfate activator (saposin B) is a small protein involved in glycosphingolipid metabolism. It binds certain membrane lipids, making them available to water-soluble enzymes. Defects in this protein are responsible for a form of metachromatic leukodystropy, a progressive neurodegenerative
โฆ LIBER โฆ
The cerebroside sulfate activator from pig kidney: Derivitization, cerebroside sulfate binding, and metabolic correction
โ Scribed by Arvan L. Fluharty; William E. Meek; Zoltan Katona; Katherine K. Tsay
- Book ID
- 113382973
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 797 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0885-4505
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The specific sugar residues and their linkages in the oligosaccharides from pig kidney and human urine cerebroside sulfate activator proteins (saposin B), although previously hypothesized, have been unambiguously characterized. Exhaustive sequential exoglycosidase digestion of the trimethyl-p-aminop