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The cerebro-hepato-renal (Zellweger) syndrome. Impaired de novo biosynthesis of plasmalogens in cultured skin fibroblasts

โœ Scribed by G. Schrakamp; R.B.H. Schutgens; R.J.A. Wanders; H.S.A. Heymans; J.M. Tager; H. Van den Bosch


Book ID
115739329
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
553 KB
Volume
833
Category
Article
ISSN
0005-2760

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Deficiency of plasmalogens in the cerebr
โœ H. S. A. Heymans; H. v. d. Bosch; R. B. H. Schutgens; W. H. H. Tegelaers; J. -U. ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 876 KB

We have analyzed the phospholipid composition of various organs of patients with the cerebro-hepato-renal (Zellweger) syndrome. The phospholipid composition of tissues from controls and patients was very similar except for their plasmalogen contents. In controls about 50% of the phosphatidylethanola