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The central role of fat and effect of peroxisome proliferator-activated receptor–γ on progression of insulin resistance and cardiovascular disease

✍ Scribed by Willa A Hsueh; Ronald Law

Book ID: 113976775
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 188 KB
Volume: 92
Category: Article
ISSN: 0002-9149
DOI: 10.1016/s0002-9149(03)00610-6

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## Abstract Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) plays a critical role in glucose and lipid metabolism. More recently, PPAR‐γ ligands have been reported to inhibit the expression of proinflammatory molecules by monocytes/macrophages. Of relevance to CNS disease is that PPAR‐γ agoni