The CELO adenovirus Gam1 protein enhances transient and stable recombinant protein expression in Chinese hamster ovary cells
β Scribed by David L. Hacker; Elisabeth Derow; Florian M. Wurm
- Book ID
- 118471262
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 221 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0168-1656
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## Abstract An expression vector was specifically designed for use in Chinese hamster ovary (CHO) cells to enhance the level of protein production in a transient expression system. Two key components that can increase protein production transiently are the promoter used to drive recombinant gene ex
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells, are widely exploited as hosts for the production of recombinant proteins, but often yields are limiting. Such limitations may be due in part to the misfolding and subsequent degradation of the heterologous proteins. Consequent