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The cellular basis for the ia restriction in murine experimental autoimmune thyroiditis

✍ Scribed by William V. Williams; Michael Kyriakos; Gordon C. Sharp; Helen Braley-Mullen


Book ID
113133836
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
856 KB
Volume
110
Category
Article
ISSN
0008-8749

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Experimental autoimmune thyroid disease (EAT) can be induced experimentally in mice following immunization with mouse thyroglobulin (mTg) and the adjuvants lipopolysaccharide (LPS) or complete Freund's adjuvant (CFA). EAT can also be transferred to naive recipients by CD4 + T cells from mTg-primed m