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The Cell of Origin ofBRCA1Mutation-associated Breast Cancer: A Cautionary Tale of Gene Expression Profiling

✍ Scribed by Gemma Molyneux; Matthew J. Smalley


Publisher
Springer US
Year
2011
Tongue
English
Weight
123 KB
Volume
16
Category
Article
ISSN
1083-3021

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## Abstract Mutations in __ATM__ are responsible for the autosomal recessive disorder ataxia telangiectasia. Heterozygous mutations in __ATM__ have been associated with an elevated risk of breast cancer. We previously reported one breast cancer family in which __ATM__ 7271T>G (V2424G) segregated wi