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The cell cycle as a therapeutic target for Alzheimer's disease

✍ Scribed by Rachael L. Neve; Donna L. McPhie


Book ID
113845694
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
391 KB
Volume
111
Category
Article
ISSN
0163-7258

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The pathology of Alzheimer's disease (AD) is characterized by cerebral atrophy in frontal, temporal, and parietal regions, with senile plaques, dystrophic neurites, and neurofibrillar tangles within defined areas of the brain. Another characteristic of AD is regional hypometabolism in the brain. Thi