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The CDKN2A p.A148T variant is associated with cutaneous melanoma in Southern Brazil

✍ Scribed by Renato M. Bakos; Robert Besch; Gabriela G. Zoratto; Janaína M. Godinho; Nicolle G. Mazzotti; Thomas Ruzicka; Lucio Bakos; Sidney E. Santos; Patricia Ashton-Prolla; Carola Berking; Roberto Giugliani


Book ID
111244924
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
204 KB
Volume
20
Category
Article
ISSN
0906-6705

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## Abstract Cutaneous malignant melanoma (CMM) is an etiologically heterogeneous disease with genetic, environmental (sun exposure) and host (pigmentation/nevi) factors and their interactions contributing to risk. Genetic variants in DNA repair genes may be particularly important since their altere