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The CD45 isoform B220 identifies select subsets of human B cells and B-cell lymphoproliferative disorders

✍ Scribed by Scott J. Rodig; Aliakbar Shahsafaei; Betty Li; David M. Dorfman

Book ID
116533864
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
672 KB
Volume
36
Category
Article
ISSN
1532-8392

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## Abstract ## Background Differences between human and murine B cells exist at all stages of B‐cell development, including the stage of memory B‐cell formation. B cells in mice are identified with the pan–B‐cell–specific CD45 isoform, B220. In initial studies in humans, it appeared that B220 expr