𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The CD2 and CD28 adhesion molecules induce long-term autocrine proliferation of CD4+ T cells

✍ Scribed by Régis Costello; Chantal Cerdan; Christine Pavon; Hervé Brailly; Christian Hurpin; Claude Mawas; Daniel Olive

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
629 KB
Volume
23
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Signals involved in T cell activation. T
Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti-CD28 and anti-CD2 monoclonal antibodies
✍ René A. W. Van Lier; Miranda Brouwer; Lueien A. Aarden 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 654 KB

Monoclonal antibodies (mAb) directed against the T cell differentiation antigen CD28 (Tp44) induce proliferation of resting T lymphocytes in the presence of phorbol esters. Moreover, it has been reported that such antibodies augment and sustain T cell proliferation induced by soluble antigens, phyto

A fundamental difference in the capacity
A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules
✍ Yumi Yashiro; Xu-Guang Tai; Kazuhito Toyo-oka; Cheung-Seog Park; Ryo Abe; Toshiy 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB 👁 2 views

T cell activation requires two signals: a signal from the TCR and a co-stimulatory signal provided by antigen-presenting cells (APC). In addition to CD28, multiple molecules on the T cell have been described to deliver co-stimulatory signals. Here, we investigated whether there exist quantitative or

Expression of cell interaction molecules
Expression of cell interaction molecules by immature rat thymocytes during passage through the CD4+8+ compartment: developmental regulation and induction by T cell receptor engagement of CD2, CD5, CD28, CD11a, CD44 and CD53
✍ Rita Mitnacht; Michael Tacke; Thomas Hünig 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 564 KB

Rat thymocytes of the T cell receptorlow (TcRIOW) CD4+8+ subset which is the target of repertoire selection are heterogeneous with respect to expression of the cell interaction (CI) molecules CD2, CD5, CDlldCD18 (LFA-l), CD28 and CD44. We show that this heterogeneity is due to the developmental regu

The role of lymphocyte subsets and adhes
The role of lymphocyte subsets and adhesion molecules in T cell-dependent cytotoxicity mediated by CD3 and CD28 bispecific monoclonal antibodies
✍ Christoph Renner; Wolfram Jung; Ugur Sahin; Rene van Lier; Michael Pfreundschuh 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 776 KB

## Abstract The cure of human Hodgkin's tumors heterotransplanted into SCID mice can be achieved by two bispecific monoclonal antibodies (Bi‐mAb) directed against the tumor‐associated CD30 antigen and CD3 and CD28, respectively, and normal peripheral human blood T cells. We investigated the role of