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The CCK-A receptor antagonist devazepide but not the CCK-B receptor antagonist L-365,260 reverses the effects of chronic clozapine and haloperidol on midbrain dopamine neurons

โœ Scribed by Yoshio Minabe; Charles R. Ashby Jr.; Rex Y. Wang


Book ID
115801719
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
341 KB
Volume
549
Category
Article
ISSN
0006-8993

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Extracellular single-unit recording techniques were used to study the effects of the cholecystokinin-A (CCK-A) antagonist, L-364,718, and the CCK-B antagonist, PD 134308, on DA neuronal activity in chloral hydrate anesthetized rats. Neither L-364,718 (0.1-1.6 m g k g i.v.) nor PD 134308 (0.1-6.4 mgk