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The causes of reduced proton-pumping efficiency in type B and C respiratory heme-copper oxidases, and in some mutated variants of type A

✍ Scribed by Rauhamäki, Virve; Wikström, Mårten


Book ID
121749962
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
469 KB
Volume
1837
Category
Article
ISSN
0005-2728

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von Willebrand Disease (vWD) is the most frequently inherited bleeding disorder in humans, and is caused by a qualitative and/or quantitative abnormality of the von Willebrand factor (vWF). A large number of defects that cause qualitative variants have been located in the A1 domain of the vWF, which