Direct incorporation of unprotected keto
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Lisa A. Marcaurelle; Carolyn R. Bertozzi
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Article
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1998
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Elsevier Science
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French
⚖ 245 KB
An amino acid bearing an unprotected ketone group, (2S)-aminolevulinic acid, was incorporated into a synthetic peptide using standard Fro©c-based solid-phase methods. The ketone group remained unharmed during the synthesis and provided a uniquely reactive functional group for covalent modification o