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The Catalytic Subunit of Dictyostelium cAMP-Dependent Protein Kinase : Role of the N-Terminal Domain and of the C-Terminal Residues in Catalytic Activity and Stability

✍ Scribed by Lilian C. Etchebehere; Miguel X. P. Van Bemmelen; Christophe Anjard; François Traincard; Karine Assemat; Christophe Reymond; Michel Veron


Book ID
115133894
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
879 KB
Volume
248
Category
Article
ISSN
1432-1327

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## Abstract A novel mutant of the catalytic α subunit of human protein kinase CK2 (CK2α) was designed in an attempt to clarify the role of the carboxylic‐terminal segment characteristic of vertebrates, excluding fish. Starting from the sequence alignments, we constructed a phylogenetic tree of the