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The carrier rate and mutation spectrum of genes associated with hearing loss in South China hearing female population of childbearing age

✍ Scribed by Aihua Yin, Chang Liu, Yan Zhang, Jing Wu, Mingqin Mai, Hongke Ding…


Book ID
120679316
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
147 KB
Volume
14
Category
Article
ISSN
1471-2350

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Hereditary hearing loss (HHL) is one of the most common congenital disorders and is highly heterogeneous. Mutations in the connexin 26 (CX26) gene (GJB2) account for about 20% of all cases of childhood deafness, and approach 50% in documented recessive cases of non-syndromic hearing loss. In additio