The Cardiovascular Effects of Ricin in Rabbits
β Scribed by Christiansen, Victoria J. ;Hsu, Chia-Hsuh ;Dormer, Kenneth J. ;Robinson, Casey P.
- Book ID
- 114802170
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 465 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0901-9928
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Ricin, a toxic lectin from the castor bean, affects the cardiovascular system. Because calcium is very important in cardiotoxicity and cell intoxication, we studied the effects of ricin pretreatment to rabbits on basal intracellular calcium levels and calcium uptake and release from isolated papilla
Ricin is a toxic lectin that inhibits protein synthesis. Because ricin decreases arterial pressure and causes cardiovascular collapse, its effects on the vascular neuroeffector system were investigated. Rabbits were given either of two doses of ricin, and then norepinephrine WE) release from aorta t