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The Cardiovascular Effects of Ricin in Rabbits

✍ Scribed by Christiansen, Victoria J. ;Hsu, Chia-Hsuh ;Dormer, Kenneth J. ;Robinson, Casey P.


Book ID
114802170
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
465 KB
Volume
74
Category
Article
ISSN
0901-9928

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Ricin, a toxic lectin from the castor bean, affects the cardiovascular system. Because calcium is very important in cardiotoxicity and cell intoxication, we studied the effects of ricin pretreatment to rabbits on basal intracellular calcium levels and calcium uptake and release from isolated papilla

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Ricin is a toxic lectin that inhibits protein synthesis. Because ricin decreases arterial pressure and causes cardiovascular collapse, its effects on the vascular neuroeffector system were investigated. Rabbits were given either of two doses of ricin, and then norepinephrine WE) release from aorta t