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The Cardiovascular Effects of Peroxisome Proliferator-activated Receptor Agonists

✍ Scribed by Sayuri N. Friedland; Aaron Leong; Kristian B. Filion; Jacques Genest; Iliana C. Lega; Salvatore Mottillo; Paul Poirier; Jennifer Reoch; Mark J. Eisenberg

Book ID: 116213247
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 317 KB
Volume: 125
Category: Article
ISSN: 1555-7162
DOI: 10.1016/j.amjmed.2011.08.025

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## Abstract Peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) plays a critical role in glucose and lipid metabolism. More recently, PPAR‐γ ligands have been reported to inhibit the expression of proinflammatory molecules by monocytes/macrophages. Of relevance to CNS disease is that PPAR‐γ agoni