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The carboxyl-terminal zinc-binding domain of the human papillomavirus E7 protein can be functionally replaced by the homologous sequences of the E6 protein

✍ Scribed by Kreton O Mavromatis; D.Leanne Jones; Rupa Mukherjee; Carole Yee; Miranda Grace; Karl Münger


Book ID
117366410
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
145 KB
Volume
52
Category
Article
ISSN
0168-1702

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## Abstract Continuous expression of the human papillomavirus (HPV) oncoproteins E6 and E7 is required for the growth of cervical cancer cell lines. So far, only the overexpression of the wild type papillomavirus E2 protein has been shown to induce growth arrest in HPV18‐positive HeLa cells by repr