Structure of the carboxy-terminal PH dom
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Jackson, S. G. ;Zhang, Y. ;Bao, X. ;Zhang, K. ;Summerfield, R. ;Haslam, R. J. ;J
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Article
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2006
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International Union of Crystallography
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English
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Pleckstrin is an important intracellular protein involved in the phosphoinositide-signalling pathways of platelet activation. This protein contains both N- and C-terminal pleckstrin-homology (PH) domains (N-PH and C-PH). The crystal structure of C-PH was solved by molecular replacement and refined a