Junipal (I), a neutral metabolite isolated from Daedalea juniperina Murr., has been known' for twenty years and, until recently, represented the only known fungal polyacetylenic thiophen. Re-investigation of the fungus has however revealed' the presence of two further thiophens (II, R = CH(OH)CH3) a
The carbon-13 nuclear magnetic resonance spectrum of siderin
β Scribed by Roy D. Lapper
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 196 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Recently the fungal metabolite 4,7-dimethoxy-5-methyl coumarin (I) has been isolated' from the petroleum ether extract of Aspergillus varieoolor (IWI 53749). Its structure has been established by chemical and spectroscopic methods and by the carbon-13 nmr investigation reported here. Its synthesis has also been achievedlV3. This compound, which has been given the trivial name, siderin 293, has been reported to occur in the plants Sideritis,canariensis2 3 and Sideritis romana , and Buchi et al.
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The =C chemical shifts of a series of isoflavones having hydroxy, acetoxy, methoxy and methylenedioxy substituents are compared. Some general relationships between substitution patterns and chemical shifts, useful for the identitication of naturally occurring isoflavones, are outlined.
## Abstract Carbonβ13 NMR chemical shifts are reported for six angular and one linear dichloropyridoquinolines in CDCl~3~. The chemical shift assignments have been made using model compounds, fully coupled spectra, selective proton decoupling and results from lanthanide shift studies. Chlorine subs