Hereditary nonpolyposis colorectal cancer (HNPCC) results from an inherited defect in one of the genes responsible for repair of errors that occur during DNA replication. Affected individuals have high risk for cancers of the colon and certain extracolonic sites. It appears that HNPCC patients form
โฆ LIBER โฆ
The cancer potential of colorectal adenomas
โ Scribed by Robert Turell
- Book ID
- 118836578
- Publisher
- Elsevier Science
- Year
- 1962
- Tongue
- English
- Weight
- 218 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0002-9610
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## Hyperplastic polyps and serrated adenomas of the colorectum show mixed gastrointestinal differentiation, expressing both gastric (M1 or MUC5AC) and intestinal (MUC2) mucins. They also share the phenotype of mild DNA microsatellite instability (MSI-L). Recent findings of clonal genetic changes wi
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