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The calpain—calpastatin system is regulated differently during human neuroblastoma cell differentiation to Schwannian and neuronal cells

✍ Scribed by Yumiko Saito; Takaomi C. Saido; Kimihiko Sano; Seiichi Kawashima


Book ID
115929524
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
540 KB
Volume
353
Category
Article
ISSN
0014-5793

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Calpains have importance in human neurodegenerative disease pathogenesis, but these mechanisms are difficult to study in postmortem tissues. To establish a cellular model of the human calpain and calpastatin system, we characterized calpain I, calpain II, and calpastatin in SH-SY5Y human neuroblasto