We report a simple method for measuring partial specific volumes. of polymers in This method has been ap-The residue volumes deduced from these The discrepancy is dilute solutions with an accuracy of 3 parts per thousand. plied to 7 polypeptides in 4 organic solvents. data are compared to those c
The calculation of partial specific volumes of proteins in 8 m urea solution
β Scribed by V. Prakash; Serge N. Timasheff
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 473 KB
- Volume
- 117
- Category
- Article
- ISSN
- 0003-2697
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π SIMILAR VOLUMES
Partial spec$c uolumes at 25Β°C are reported for a-chymotrypsinogen in aqueous solutions containing NaCI, citrate, and/or polyethylene glycol (PEG) ouer a range of protein concentrations. The concentration dependence of the partial specific uolume can be either positive or negatiue, depending on the
using partial molar volume data, V t , in aqueous solution at 25Β°C for some peptides of sequence Gly-X-Gly, where X is an amino acid. These side-chain partial molar volumes are critically compared with those obtained using V data for amino acids. It is concluded that side-chain partial molar volumes
## Abstract In the calculation of partial atomic charges, for use in molecular mechanics or dynamics simulations, it is common practice to select only a single conformation for the molecule of interest. For molecules that contain rotatable bonds, it is preferable to compute the charges from several