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The CAG repeat within the androgen receptor gene and benign prostatic hyperplasia

โœ Scribed by Edward Giovannucci; Elizabeth A Platz; Meir J Stampfer; Andrew Chan; Krishna Krithivas; Ichiro Kawachi; Walter C Willett; Philip W Kantoff

Book ID
118207537
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
139 KB
Volume
53
Category
Article
ISSN
0090-4295

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BACKGROUND. CAG repeat length in exon 1 of the androgen receptor (AR) gene correlates inversely with transcriptional transactivation activity of the AR. Men with shorter AR CAG repeat lengths are at higher risk of prostate cancer. Because benign prostatic hyperplasia (BPH) is an androgen-dependent c

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## Background: The androgen receptor (ar) gene has a polymorphic cag microsatellite encoding variable-length glutamine repeats in the ar protein. the purpose of this study was to evaluate the association between the growth of benign prostatic hyperplasia (bph) and the ar gene cag repeat length. ##