We report on two adolescent boys with Kenny-Caffey syndrome and microorchidism. The first patient had elevated levels of serum follicle-stimulating hormone, but normal levels of luteinizing hormone and testosterone. There was no evidence of a microdeletion of the Y chromosome. The second patient had
The Caffey Syndrome
✍ Scribed by Richard O’Brien
- Publisher
- Elsevier
- Year
- 1976
- Tongue
- English
- Weight
- 276 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0015-7368
No coin nor oath required. For personal study only.
✦ Synopsis
failure; the detection of Barr bodies in interphase nuclei from hair-root cells.
The monograph is written in a straightforward style and its author is clearly completely au fait with his subject. The difficulties likely to be encountered, the importance of operator experience and the necessity for correct and adequate microscopical techniques are emphasised. The author strongly recommends that hair-root rather than buccal epithelial cells should be used for sexing. Some statistics of the proportion of correct results to be expected are given. Postmortem changes are said to have little effect on the fluorescent staining properties of nuclei. There is a bibliography of nearly 200 references.
I n this reviewer's opinion (for what, with the warning already given, it is worth) this monograph, or a translation of it, should be studied by anyone concerned with, but less than vastly experienced in, the problems of nuclear sexing.
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