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The C-wave in hereditary degenerations of the ocular fundus

✍ Scribed by J. Röver; M. Bach

Publisher: Springer-Verlag
Year: 1985
Tongue: English
Weight: 282 KB
Volume: 60
Category: Article
ISSN: 0012-4486
DOI: 10.1007/bf00158027

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✦ Synopsis

The c-wave of the human direct current ERG may give new insights about the involvement of the retinal pigment epithelium in hereditary degenerations. In our singlesweep recordings from 236 alert patients we saw reduced c-waves not only in vitelliforme macular degenerations but also in dominantly inherited drusen, Stargardt's disease, cone dystrophies, and x-linked retinoschisis. In achromatopsia the c-wave was close to normal.

The relationship of the b-and c-wave, however, was altered only in Best's disease, cone dystrophy, and x-linked retinoschisis.

We postulate that the c-wave when more severely reduced than the b-wave reflects not merely the dysfunction of the pigment epithelium but more precisely whether this retinal layer is involved earlier than the photoreceptors.

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