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The C-terminal half of secretin and VIP interacts with the N-terminal domain of their receptors

Book ID
116104698
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
84 KB
Volume
64
Category
Article
ISSN
0167-0115

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Ab initio modelling of the N-terminal do
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G protein coupled receptors of the secretin family are activated by peptide hormones of about 30 residues in length. There is considerable sequence homology within both the hormone and receptor families. The receptors possess in addition to the integral membrane domain a characteristic extracellular