The association between the SH2-containi
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Sheela Onnockx; Julie De Schutter; Marianne Blockmans; Jingwei Xie; Christine Ja
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Article
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2007
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John Wiley and Sons
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English
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## Abstract SHIP2 (SH2โcontaining inositol polyphosphate 5โphosphatase 2) is a phosphatidylinositol (3,4,5)โtrisphosphate (PtdIns(3,4,5)P~3~) 5โphosphatase containing various motifs susceptible to mediate proteinโprotein interaction. In cell models, SHIP2 negatively regulates insulin signalling thr