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The C-4 Hydroxyl Group of Galactopyranosides Is the Major Determinant for Ligand Recognition by the Lactose Permease of Escherichia coli †

✍ Scribed by Sahin-Tóth, Miklós; Lawrence, Mary C.; Nishio, Toshiyuki; Kaback, H. Ronald


Book ID
126306210
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
113 KB
Volume
40
Category
Article
ISSN
0006-2960

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A conformational change in the lactose p
✍ Heinrich Jung; Kirsten Jung; H. Ronald Kaback 📂 Article 📅 1994 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 607 KB

## Abstract Lactose transport in membrane vesicles containing lactose permease with a single Cys residue in place of Val 315 is inactivated by __N__‐ethylmaleimide in a manner that is stimulated by substrate or by a H^+^ electrochemical gradient (δμ, Sahin‐Tóth M, Kaback HR, 1993, __Protein Sci 2__