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The Bsmoc Group as a Novel Scaffold for the Design of Irreversible Inhibitors of Cysteine Proteases.

✍ Scribed by Jim Iley; Rui Moreira; Luisa Martins; Rita C. Guedes; Claudio M. Soares


Publisher
John Wiley and Sons
Year
2006
Weight
14 KB
Volume
37
Category
Article
ISSN
0931-7597

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Compound 10b, 6-acetamido-6,8-dideoxy-D-erythro-beta-D- galacto-octopyranosyl-1-oxyacetic acid sodium salt, was synthesised by hydrazinolysis of Lincomycin, acetylation of methylthiolincosaminide (MTL) 9a, and by subsequent glycosylation of acetate 9b with methyl glycolate under mild conditions (NIS