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The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells

✍ Scribed by Vishwanie Budhram-Mahadeo; Peter Morris; Daniel Ndisang; Shazia Irshad; Guilermina Lozano; Barbara Pedley; David S Latchman


Book ID
117473099
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
114 KB
Volume
334
Category
Article
ISSN
0304-3940

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The Brn-3b POU family transcription fact
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## Abstract The Brn‐3b transcription factor has been shown to be overexpressed in human breast cancer cells and contributes toward cell growth regulation. Using micro‐arrays, more than 50 cancer‐related genes regulated by Brn‐3b in human breast cancer cells have been identified. For example, Brn‐3b