The borderland between benign and malignant surface epithelial ovarian tumors. Current controversy over the nature and nomenclature of “borderline” ovarian tumors

Genetic alterations in the peritumoral s

Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p

✍ Hanna Tuhkanen; Maarit Anttila; Veli-Matti Kosma; Seppo Ylä-Herttuala; Seppo Hei 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 366 KB 👁 1 views

## Abstract Stromal accumulation of hyaluronan in epithelial ovarian cancers is an independent predictor of tumor spreading and unfavorable outcome of the disease. We started to screen for chromosomal causes of this accumulation by studying deletions in 3p21.3, a region harboring 3 hyaluronidase ge